Protein Info for DVU3004 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: radical SAM domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 574 PF04055: Radical_SAM" amino acids 274 to 426 (153 residues), 59.7 bits, see alignment E=4.1e-20 PF13186: SPASM" amino acids 492 to 553 (62 residues), 30.5 bits, see alignment E=3.6e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU3004)

Predicted SEED Role

"Molybdenum cofactor biosynthesis protein MoaA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q726V2 at UniProt or InterPro

Protein Sequence (574 amino acids)

>DVU3004 radical SAM domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MNASRSLPPVIIQATNIAPLRGKHLLPLVEGRTVIEVLIGRLRGIWHDDICVATSDLPDD
DALCAHVAALGAQVVRGPHRDLVKRLILAAEAMHCDHFVRVMGAAPFVCIPRLADLAAEH
AERGVEFSYNEHRMGVPRGLGGQVVSVDMLKRLDAADISAEVRQEFAYSVLQNAEHFAVH
RQDSDLPRLALDFHLETTKDLSLLREIAVNVPDVTIEAIIDYAAQHPALHTLSRAFPPKE
VGLEKLFLHPEKILALTSQNGLPDASFPVSVELSLTNRCNLACVWCSDKDLRGRQGVKAT
LSLDTVRRLTHELREGGTKGIVIEGGGEPTLHPDFAAIVACITDAGMGAGLITNGVVTLP
PDVLRRLDWVRVSLDSSTRAEFQNAKGRDAFETVMGNIAHFARHCPTVGIGYVVTRHNTE
HLESLVLRARQAKASYIQFRPVIDAPDIAPEDFNLDYLKLFETDGFCVNTDAMRDNQVRG
NSNLPCRAHPLTSVIGADGSVHLCGRLNIFDWFEPIGNINEQSFGDIWRGAKRKSAAKAL
ADPGFCGQWCPECRITKFNQLLWRLSQSRTRNFI