Protein Info for DVU2990 in Desulfovibrio vulgaris Hildenborough JW710

Name: moeA
Annotation: molybdopterin biosynthesis MoeA protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 PF03453: MoeA_N" amino acids 16 to 166 (151 residues), 119.6 bits, see alignment E=1.6e-38 PF00994: MoCF_biosynth" amino acids 180 to 318 (139 residues), 91.5 bits, see alignment E=6.4e-30 PF12727: PBP_like" amino acids 426 to 616 (191 residues), 269.6 bits, see alignment E=1.5e-84

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA K07219, putative molybdopterin biosynthesis protein (inferred from 100% identity to dvu:DVU2990)

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA / Periplasmic molybdate-binding domain" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q726W6 at UniProt or InterPro

Protein Sequence (650 amino acids)

>DVU2990 molybdopterin biosynthesis MoeA protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSEPRRNIYLRTLPIEDAVTRARTALDRDALMHTETVPAHEAAGRVLAAPVYARFSSPTF
HSAAMDGIAVSAAKTYTAREGSPLTLALDADYRPVNTGHPMPEGCDAVIMIEQVVPVDDT
HVQIESPAFPWQHVRRLGEDIVATELLFPRNHPLNAYDVGTLLSGGIWEVEVWEKVRVRI
IPTGDEVLDFTLRPEPGAGQVVESNSQVLATMARGLGCSVERIAPVRDDPEALHAALRDS
LDAGTHLTIFCAGSSAGSKDFTRATIEREGEVLVHGIAAMPGKPSLLGVCRGRLVAGAPG
YPVSSVVCFEELLTPLLTWLSRRQSQARPVVEVELTRKVPSRLGIDEFLRLSVGRVGDKL
VGTPLARGAGNITTLSRAQAVARIPAAAEGAEGHERLTAELTVPPALLDRIVVCVGSHDN
TLDLLADELMGRDDPFRLASTHVGSMGGINALRNGSCHFAGAHLFDPETGDYNFPFIARF
LEGVPVTVVNLAIRHQGLIVAPGNPMGIQGVQDLARKGVRFINRQRGAGTRILLDWHVRE
AGISPAEVAGYDKEEYTHMAVAANVLTGAADCGLGIHAAAKALGLDFVPLARERYDLLIP
NAFLEEPRVRAVLDLLHTPAFAERIGNLGGYETTLMGRVMHPGDGLGDMG