Protein Info for DVU2887 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: membrane protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 65 to 83 (19 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 151 to 167 (17 residues), see Phobius details amino acids 187 to 204 (18 residues), see Phobius details amino acids 213 to 236 (24 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 279 to 296 (18 residues), see Phobius details amino acids 302 to 319 (18 residues), see Phobius details PF00892: EamA" amino acids 36 to 166 (131 residues), 72 bits, see alignment E=2.9e-24 amino acids 202 to 317 (116 residues), 72 bits, see alignment E=2.8e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2887)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q727G8 at UniProt or InterPro

Protein Sequence (322 amino acids)

>DVU2887 membrane protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MERDTVLTATPTIDADLADATSCATPSRTAVSPLLPVLAALAAVVLWGGAFPAMKVAVQT
LGTWQMMWARMVFALLLLVPLARRLAPARIERRDLPLLAGMALMQPCLYFLCESTALQLT
TSSQAGVMAASMPLMMAVGGFLLGEKVSPRLWFGVGVSCIGVAWLTSSGGEGGGSAPDPF
TGNLLELAAMACATGSSLCIGALISRGKGRWNALTLTGIQTLAGAVFFLPGAPGVIGGVA
DWSTEVLLAVVYLGGASSLGAFGLYNWALGHMPASRAGNFINLVPVAAIFFGWLLLGETL
TTTQYLATGLVMGGVLMGTRAR