Protein Info for DVU2679 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: sensory box histidine kinase/response regulator (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1005 PF13188: PAS_8" amino acids 43 to 108 (66 residues), 14.8 bits, see alignment 7.5e-06 amino acids 179 to 211 (33 residues), 20.9 bits, see alignment (E = 9e-08) amino acids 297 to 358 (62 residues), 23.1 bits, see alignment 1.9e-08 TIGR00229: PAS domain S-box protein" amino acids 175 to 296 (122 residues), 28.2 bits, see alignment E=8.6e-11 amino acids 326 to 416 (91 residues), 30.9 bits, see alignment E=1.3e-11 PF08448: PAS_4" amino acids 183 to 292 (110 residues), 41.6 bits, see alignment E=4.7e-14 amino acids 324 to 412 (89 residues), 26.6 bits, see alignment E=2.1e-09 PF13426: PAS_9" amino acids 194 to 289 (96 residues), 17.7 bits, see alignment E=1.2e-06 amino acids 323 to 364 (42 residues), 15.2 bits, see alignment (E = 7.7e-06) PF00512: HisKA" amino acids 633 to 698 (66 residues), 74.4 bits, see alignment 2.2e-24 PF02518: HATPase_c" amino acids 744 to 859 (116 residues), 98.4 bits, see alignment E=1.2e-31 PF00072: Response_reg" amino acids 883 to 995 (113 residues), 86 bits, see alignment E=7.1e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2679)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728C4 at UniProt or InterPro

Protein Sequence (1005 amino acids)

>DVU2679 sensory box histidine kinase/response regulator (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MARRKDKQHRARMVQAESTIRTLRRERVLHDSQVEQLRRTGALYRSVFERIPVMVFVWRV
ARDVGASRLIDMNPLAKAYLENVPRNGDDGSPDLPESPDLLGSLLPWLVESPFGEALRRV
HAEGGTLEIPALRHGAAGGGRFWRCIFCRLPLGDVIAISEDITAAQETGAALVTSERGYR
TLVENIPDIVVRFDARGRLLFANPALRRFVRSKRLPSGHVTGQPLGQQPAMLRELRERVQ
LAMSSGEVQRAELEERTRQGRRFFEWRIVPEPAPDGGDATVLCIGRDVSAMRRATEDYRA
LFNGMLSAFALHEIICDGAGVPVDYRFLAVNPAFERMTGLLASEMVGRTARDVLPGLESE
WLQRYGQVALTGVPVTFEAFNRDLGKYFKVSAYRPAERQFACMFHDVTDRVRGREERRSN
ARRMAALQRIFRMKEPEEVVARYALTQSMQLTGARVGRVVLHDPETRVIRHIVDHGDPLF
GTEGWQWASVAHGGAGGDDTDGGAAGGRGPDEPEGIAGPRRVPPQPDAGHVAEPDRARLD
DLMTRAAAGMGPLASELTHGRHGPHARHLAVPVRLDGRLGAVAVLLDKPTPFTRADIKQL
DLLMRGMLEHLERRRSLHRLSLAKEHAESANRAKSEFLANMSHELRTPLNGMLGMLQLLE
AGDLDRDQNELVHIALDSGRTLLRVLSDILDLSRIEAGRMELRHDRFSPEEAVRQVYDMF
AQDARIRGLRLRWRCDELPCEVWGDGTRLRQILFNLLGNAMKFTHEGTVGVEVCAVRRTE
ESVRLLFSVSDTGIGIPHDRLMSIFEPFTQLDGSTTRRYSGTGLGLGIVRRLVHLMGGGL
NVESALGEGTAVHVCLPFRLPSGGGVTCDVMDSTPALRRPLKVLVAEDEAVNRMTLSRCL
HHLGHEAVCVTNGLEAVEALREGRFDCVLMDIQMPELDGLEALARIRAEAGEQARALPPV
VALTAHAMEGDRERFLAAGMSAYIPKPIELGELERVLLRLAAAMP