Protein Info for DVU2655 in Desulfovibrio vulgaris Hildenborough JW710

Name: dacA
Annotation: D-alanyl-D-alanine carboxypeptidase family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF00768: Peptidase_S11" amino acids 40 to 261 (222 residues), 215 bits, see alignment E=1.2e-67 PF13354: Beta-lactamase2" amino acids 49 to 187 (139 residues), 57.7 bits, see alignment E=1.1e-19

Best Hits

KEGG orthology group: K07258, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) [EC: 3.4.16.4] (inferred from 100% identity to dvl:Dvul_0599)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728E8 at UniProt or InterPro

Protein Sequence (441 amino acids)

>DVU2655 D-alanyl-D-alanine carboxypeptidase family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MAHQSIPGHGKRFPGQLGIVLLVLTFVVASVCGAHASERLNVVSAFLIDQNSRRVLFEQN
ADAQIPPASLTKVISMYVALDHIRAGKASLADKVKISARAARTGGSRMFLTRGETVSLDE
LLMGMAVSSGNDASVAVAEHIAGSTDRFVQLMNAKARALGMTETTFRNVNGLPAAGQKTT
ARDMGKLAVSYLTAHPQALRYHSTRFIRHNKVITTNKNPMLGNCEGADGLKTGWVCASGY
NLISTVKRGNTRLVAVVLGAENSQVRGQEMNRLIDAGYRSLRGEGPSVAAVLPRLSPADY
RIDLHKTNSLAYAEVSKHKKKIAARKGKLRAGKTGSKQHASAQVSKSSKSSKAVKGKSPD
KSAATSKAVATVRREKAKAVPSNKSVRATKVQQARKAAVARKTETKTTVKRSKPATAAST
KKTAAPPRTPVQRAERTDKRG