Protein Info for DVU2568 in Desulfovibrio vulgaris Hildenborough JW710
Name: cpsA
Annotation: peptidase, M20/M25/M40 family (TIGR)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 44% identical to YTNL_BACSU: Uncharacterized hydrolase YtnL (ytnL) from Bacillus subtilis (strain 168)
KEGG orthology group: K01436, amidohydrolase [EC: 3.5.1.-] (inferred from 100% identity to dvu:DVU2568)MetaCyc: 44% identical to N-acetyl-L-cysteine deacetylase (Bacillus subtilis subtilis 168)
3.5.1.-
Predicted SEED Role
"N-acetyl-L,L-diaminopimelate deacetylase homolog (EC 3.5.1.18)" (EC 3.5.1.18)
MetaCyc Pathways
- aspartate superpathway (20/25 steps found)
- L-lysine biosynthesis I (7/9 steps found)
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (13/18 steps found)
- S-(2-succinyl)-L-cysteine degradation (2/4 steps found)
- S-benzyl-L-cysteine degradation (1/5 steps found)
KEGG Metabolic Maps
- 1,4-Dichlorobenzene degradation
- Caprolactam degradation
- Glutathione metabolism
- Lipopolysaccharide biosynthesis
- Lysine biosynthesis
- Nicotinate and nicotinamide metabolism
- Nucleotide sugars metabolism
- Sphingolipid metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.-, 3.5.1.18
Use Curated BLAST to search for 3.5.1.- or 3.5.1.18
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q728N5 at UniProt or InterPro
Protein Sequence (412 amino acids)
>DVU2568 peptidase, M20/M25/M40 family (TIGR) (Desulfovibrio vulgaris Hildenborough JW710) MSGHTAHSGTRHPHTGATVQRLAAEVESHIIAHRRALHAIPETGFEERCTAAYVAETLSG LGLPVRTGIATTGVTALLDTGLEGPVVMLRADMDALPVTEATGLPFASRHEGRMHACGHD AHMAMLLGAAEMLSAIVREEPGRLRGKVLFLFQPAEEGPGGAAPMIAEGVLDEPKVDVCL GAHVWPSLPVGTVGVKPGPLMAAMDRFELAVHGRGGHAATPHLCVDALETATQVVGALQR VVSRMTDPLEPVILTIGELHAGTAYNVIPGEARMAGTVRTFSPDVRAAWEDRIRTVADGV CAAMGATATLDFHYCHGPVINTPRVAEVVRRAVVEARGEQAVTTPTPTLGGEDFSCFLER IPGCFFFVGCGGDVPIHNPRFDLDERCLALGAETFVRAALLFTEGGATGMTA