Protein Info for DVU2444 in Desulfovibrio vulgaris Hildenborough JW710

Name: flaB3
Annotation: flagellin (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 PF00669: Flagellin_N" amino acids 5 to 141 (137 residues), 125.5 bits, see alignment E=1.7e-40 PF00700: Flagellin_C" amino acids 212 to 295 (84 residues), 80.6 bits, see alignment E=8.8e-27

Best Hits

Swiss-Prot: 39% identical to FLAB3_TREPA: Flagellin FlaB3 (flaB3) from Treponema pallidum (strain Nichols)

KEGG orthology group: K02406, flagellin (inferred from 100% identity to dvl:Dvul_0790)

Predicted SEED Role

"Flagellin protein FlaA" in subsystem Flagellum or Flagellum in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729A8 at UniProt or InterPro

Protein Sequence (297 amino acids)

>DVU2444 flagellin (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSLVINHNMMAMNAAGNLSNSYGKLSTSVRRLSSGLRVGTAADDAAGLAIRELMRSDISA
LNQGVRNANDAISLIQTADGALGVIDEKLIRMKELAEQAATGTYTSDQRLIIDSEYQAMA
SEITRIANATDFNGLHLLNGNLSSDTHDGSGLQSTGKMKIHFGTANDSAEDYYYVQIGTS
TASALGVGNQATAGSAGYTISTQSAAQQALVAIQNAIISKDNIRASLGALQNRLENTISN
LRTQAENLQSAESRISDVDVSSEMTEFVRQQILTQSAVAMLSQANSLPRMAMQLLGG