Protein Info for DVU2349 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: carbohydrate phosphorylase family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 855 PF11897: DUF3417" amino acids 13 to 121 (109 residues), 103.1 bits, see alignment E=1.8e-33 TIGR02094: alpha-glucan phosphorylases" amino acids 108 to 711 (604 residues), 840.5 bits, see alignment E=4.4e-257 PF00343: Phosphorylase" amino acids 271 to 621 (351 residues), 79.5 bits, see alignment E=2.8e-26 PF28476: GlgP_C" amino acids 742 to 853 (112 residues), 91.1 bits, see alignment E=1.1e-29

Best Hits

KEGG orthology group: K00688, starch phosphorylase [EC: 2.4.1.1] (inferred from 100% identity to dvl:Dvul_0912)

Predicted SEED Role

"Glycogen phosphorylase (EC 2.4.1.1)" in subsystem Glycogen metabolism or Maltose and Maltodextrin Utilization (EC 2.4.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729K1 at UniProt or InterPro

Protein Sequence (855 amino acids)

>DVU2349 carbohydrate phosphorylase family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MQPLKVFSVVPKLPEGLEGLWELAYNLWFSWNEEIAALFSQIDQQLWIESYRNPVWFLNH
VPQRALETLAQDALYKSRLREAVARQRQYLSRPAYTLKGDEGGEGIRVVYFSLEYGISLC
LPIYSGGLGILAGDHLKSASDLNVPLAAIGIAYQQGYFRQYMTPDGWQQERYPNYDFEQM
PMRPALTPDGQPAVVHLDIGDRPLKARIWRVDVGRVPLYLLDTNIAENPPDFRQITERLY
GGNNEMRLWQEMLIGIGGIKALQVLGISPKVIHMNEGHSAFAGLERVRLFMKEHGLSFEA
AVEVAAAGSIFTTHTPVPAGNDRFAPDLMARYFEPYASDMGLAFKVFMALGREVPHDDSE
PFCMPVLALRLSRFNNGVSKLHGRVSRNMWKRVWNQFPVEDVPIGALTNGVHAPTWVAPD
IGLLYDRYLGSNWREDPDSSRAWSLVDTISDAELWRTHERLRARLVDFARMRLHRQLAAQ
GARRQDIQMAEEVLNPEALTIGFARRFATYKRANLLLQERDRLIRLVTSTDRPVQFIFAG
KAHPQDQEGKQLMKELIALCRSRECRMSMVFLEDYDMEVASHLVSGCDIWLNNPRRPLEA
CGTSGMKAMLNGVMQFSTLDGWWDEAYRPDNSLGWAIGKGEEYEDPDYQDFVEVQTLYNI
LENDIIPDFYDRGHGGIPRTWVRRMKAALRELAPAFNSHRMVMDYAGTAYAPALHNFNEL
TQRDFAPARELSEWRMDIMTKWSMLQIRNVRAQQADTLHVGDALTVEAEILLNGIDPGHI
RAEIYAGHLNQDNSFAHRELSPMQHVGQTDDGWQVFRGTTAPAEAGRYGFTVRVCPTHPR
LADPHSLGLIRWAGV