Protein Info for DVU2309 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: methyl-accepting chemotaxis protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 695 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 296 to 319 (24 residues), see Phobius details PF02743: dCache_1" amino acids 60 to 283 (224 residues), 118.1 bits, see alignment E=9.7e-38 PF22673: MCP-like_PDC_1" amino acids 138 to 202 (65 residues), 31.6 bits, see alignment E=3.8e-11 PF00672: HAMP" amino acids 317 to 368 (52 residues), 28.7 bits, see alignment 2.6e-10 PF00015: MCPsignal" amino acids 476 to 659 (184 residues), 163.9 bits, see alignment E=6.7e-52

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to dvl:Dvul_0949)

Predicted SEED Role

"methyl-accepting chemotaxis sensory transducer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729P1 at UniProt or InterPro

Protein Sequence (695 amino acids)

>DVU2309 methyl-accepting chemotaxis protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTIRTKLVLAFLASIVVAIGSITTVVSLQVSKNSVAAFEESSLGQLDRTNDFIAAFLNEA
RYNAMFLAKLDEVVQAPGKITSYVNTTSAPSIRRADMQPNEQKLFDIFMHMTKGNPAYDG
VFLGTAEGGFNMFPEDSLPAGYDPRKRPWYKEALGSGEDSIISKAYMSTTRVPVSSVVAK
VFDAQRRVVGAIGIDINLSTLTRVTSALHIGQTGYVMLVEDTGIIISDPKHEQFAFKNIT
ETGTPAFTRIMGMKRGMFEDSLDGKDRIFTVVTGYLGWKLVSVIDADEVYGKARSLVFTI
VSIGFGIALVLLAVAWFIARSVAEPIRMLVEASGEVARGNFNALPSERHFSGELLTLRGS
LNDMVTQLGNLVSTAETKTQEAEEQARKAGEALTQAEEARRAGEVARREGIMQTAGRLES
IVDQITSASQELASQIGEATRGSDIQRARTTEAATAMEEMNASVLEVASNASRAAESAEH
ARKEAEGGGGIVRDVVSSIGEVNRFAAEMGGSLDDLGKQAEGIGHIMTVITDIADQTNLL
ALNAAIEAARAGEAGRGFAVVADEVRKLAEKTMTATKEVGDAIGAIQRGTRNNIDGMSRA
SGVISQSTDLASRAGDALGRIVNIVESTADQVRSIATASEEQSAASEEINRSTEEVNRIA
SEMAEAMSQSAVAVNELARLAADLQDIIRQLKEDR