Protein Info for DVU2240 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: hydantoinase/oxoprolinase family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 PF05378: Hydant_A_N" amino acids 3 to 154 (152 residues), 91.3 bits, see alignment E=6.3e-30 PF01968: Hydantoinase_A" amino acids 178 to 459 (282 residues), 145.8 bits, see alignment E=1.7e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvl:Dvul_1002)

Predicted SEED Role

"N-methylhydantoinase (ATP-hydrolyzing) (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729V7 at UniProt or InterPro

Protein Sequence (550 amino acids)

>DVU2240 hydantoinase/oxoprolinase family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MFLGIDVGGTHTDAVVMDGRRVVCSCKVPTDHHDLLSSVRQAMRTLLETVEPAAVTRINL
STTLSTNAIVEGRTEEVGVVVAGGPGIDPEHVRVGRFYQSVPGSIDHRGVEIAGIDADSL
DAVAGRYCREGVRVYAAVGKFSTRNPAHEQAIGGKLMECGDFVSMGHRLSGQLNFPRRVA
TAYYNSAVWRVYNAFADAIENAAREMGLAAPIHVLKADGGTMPLAVSREVPVESILSGPA
ASVMGIVALCDIREDCVILDVGGTTTDIAVFASGAPVIERDGIDVGSYATLVRALRTHSI
GVGGDSRLHVQAGAVRVGPERMGPSMALGGTQPTLIDALNYMGKAHVGEVEASRRGIRDL
AALWDMFPERLASEAVTTAVRRIAEAVTELVDAINARPVYTIMELLQGRRVDPVRAYVMG
GPAEVLRPLLADALGRRVDVPEQYAVANAIGAALTRTTAELELFADTEKGVLFIPTLDVR
REVGTRYDIEAAKRDAGQALLEHLASLGVDDDEAAVEVVEATSFNMVDDYGTAGRNIRVK
CQVRPGILGA