Protein Info for DVU2133 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: membrane protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 579 transmembrane" amino acids 26 to 45 (20 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 225 to 243 (19 residues), see Phobius details amino acids 250 to 271 (22 residues), see Phobius details amino acids 302 to 327 (26 residues), see Phobius details amino acids 339 to 359 (21 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 403 to 423 (21 residues), see Phobius details amino acids 435 to 454 (20 residues), see Phobius details amino acids 475 to 495 (21 residues), see Phobius details amino acids 515 to 534 (20 residues), see Phobius details amino acids 546 to 572 (27 residues), see Phobius details PF03601: Cons_hypoth698" amino acids 228 to 548 (321 residues), 148.4 bits, see alignment E=1.1e-47

Best Hits

Swiss-Prot: 100% identical to Y2133_DESVH: UPF0324 membrane protein DVU_2133 (DVU_2133) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2133)

Predicted SEED Role

"FIG00602470: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72A64 at UniProt or InterPro

Protein Sequence (579 amino acids)

>DVU2133 membrane protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MAENESNVVVDQGQTKLSDLWTKEDYWAIWLGFVILIAGMWLFLANPSPEFAQKVDKANG
VMAAEAARAPFKTLAYYKAQDDKGKLQGMDTPSGKAIGAFLTTPGAWASDPLEAFVLSKE
AADERNAAAKAKFESAKVKSDAALAAAQAAEAAAAGAAFADAALNTEAQAKIAEWRAEHA
KMKAAEKKTKTKPFNIATSLPMLMVALGLFFAVGMKFMGHDVPKFLVGFIGVFFVAVLAL
MMGHQSTMKYWGIGAEAWAIIIGMLVANTVGTPSFIKPALQVEYYIKTGLVLLGAEVLFD
KIIAIGIPGIFVAWVVTPIVLICTFIFGQKILKMPSKTLNIVISSDMSVCGTSAAIATAA
ACRAKKEELTLAIGLSLVFTAIMMIAMPAFIKAVGMPQVLGGAWMGGTIDATGAVAAAGA
FLGEKALYVAATIKMIQNVLIGVVAFGVAVYWCARVECREGHSVGWIEIWHRFPKFVLGF
LAASVLFSVISGSLGSDMSQIMVNQGVLKGLSSPLRNWFFCLAFTSIGLATNFRELAHYF
KGGKPLILYVAGQSFNLVLTLAMAYVMFYIVFPEITAKI