Protein Info for DVU2124 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: conserved hypothetical protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 transmembrane" amino acids 70 to 93 (24 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details PF00482: T2SSF" amino acids 140 to 268 (129 residues), 68.7 bits, see alignment E=2.4e-23

Best Hits

KEGG orthology group: K12511, tight adherence protein C (inferred from 100% identity to dvu:DVU2124)

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72A73 at UniProt or InterPro

Protein Sequence (284 amino acids)

>DVU2124 conserved hypothetical protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MQSRVARHLDRNAPTAAASATTLSDDMRRGINAMAERLGQRVINEGDTELTEAGMALARA
GYRNRTAPRVFWGVKAGLTVAGLLMGLTVRLLLGDDVPAGMVALLFIGPAVTGLYLPNIW
LSSRIKERRQEIINALPDALDLLVVCVEAGMGLDQALARVAKELQSTSPVLAEELQLSIL
ELRAGKSRADTLKNLAARVAIEDVNSLVTLIIQADAFGTSIASTLRVYSDTMRTTRFQRA
EEIAAKMPVKLLFPLVFCILPALFVTIMGPAFIKLMQVFAQMNQ