Protein Info for DVU2123 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: membrane protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 262 to 281 (20 residues), see Phobius details amino acids 296 to 313 (18 residues), see Phobius details PF00482: T2SSF" amino acids 154 to 278 (125 residues), 62.2 bits, see alignment E=2.5e-21

Best Hits

KEGG orthology group: K12510, tight adherence protein B (inferred from 100% identity to dvu:DVU2123)

Predicted SEED Role

"Flp pilus assembly protein TadB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72A74 at UniProt or InterPro

Protein Sequence (321 amino acids)

>DVU2123 membrane protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTLIIPILAIIAMFMLVMGLANLVTGKRRTERERIARRLGTLHGAKGDTRGVDLERKLTL
SDMPWLDDLLAAQAWTRRMALILEQGQVKTTLGMLVLTSVMAGALCLMAMALFSSNVFLL
VVPPLAVAYVPFMLVFRKRARRMARFQRQLPDALDLVGRALRAGHAFNQGMRMVADEFED
PIGPEFQKVLDEINYGVPADTALINLVRRVDCPDLKFFVVSVNIQRETGGNLAEIVTGIA
RLIRERFKLAGRVRVLSAEGRLTAWILLALPFGIGIIINMLNPDFMSVLYETPEGNLLMT
GSLFQMTIGAIALKRMTTIRV