Protein Info for DVU1950 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: indolepyruvate ferredoxin oxidoreductase, beta subunit, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 PF01558: POR" amino acids 12 to 192 (181 residues), 127.3 bits, see alignment E=3.8e-41

Best Hits

Swiss-Prot: 38% identical to IORB_METTM: Indolepyruvate oxidoreductase subunit IorB (iorB) from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)

KEGG orthology group: K00180, indolepyruvate ferredoxin oxidoreductase, beta subunit [EC: 1.2.7.8] (inferred from 100% identity to dvl:Dvul_1218)

Predicted SEED Role

"Indolepyruvate oxidoreductase subunit IorB (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72AP2 at UniProt or InterPro

Protein Sequence (198 amino acids)

>DVU1950 indolepyruvate ferredoxin oxidoreductase, beta subunit, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSRIRIYMTGVGGQGTLTATTLLARTALDAGCEVVAGEIHGMAQRGGVVESTVLLGGWQS
PKLSHGEADIVLGFEPLETLRGLPYLTAGGAVLSNAETLPPVGVSMGRESYPCLDGIREK
VTGCSGRAWFLPCRTLGLKAGSVQSGNSVLLGALCATGLLPFGVDALEAAIRRHLAPKLV
DMNLRAVELGVQAVADAS