Protein Info for DVU1897 in Desulfovibrio vulgaris Hildenborough JW710

Name: glyS
Annotation: glycyl-tRNA synthetase, beta subunit (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 TIGR00211: glycine--tRNA ligase, beta subunit" amino acids 3 to 695 (693 residues), 633.2 bits, see alignment E=4e-194 PF02092: tRNA_synt_2f" amino acids 4 to 553 (550 residues), 632.6 bits, see alignment E=7e-194 PF05746: DALR_1" amino acids 584 to 681 (98 residues), 24.2 bits, see alignment E=3e-09

Best Hits

Swiss-Prot: 100% identical to SYGB_DESVH: Glycine--tRNA ligase beta subunit (glyS) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K01879, glycyl-tRNA synthetase beta chain [EC: 6.1.1.14] (inferred from 100% identity to dvu:DVU1897)

Predicted SEED Role

"Glycyl-tRNA synthetase beta chain (EC 6.1.1.14)" (EC 6.1.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.14

Use Curated BLAST to search for 6.1.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72AU3 at UniProt or InterPro

Protein Sequence (696 amino acids)

>DVU1897 glycyl-tRNA synthetase, beta subunit (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSQFVLEIGTEELPARFLPALERELAERFTRALADAGIECDPVRVMSTPRRAVVRMDAVN
PVQSESEEVVTGPPARIAFTPEGGLTKAAEGFARTQGVEVADIFRLTTDKGEYIAVRKHM
GGARSIDLLRDICPAIIGALPFPKRMRWGSGDFTYARPMRWLLALFDESVVDFEVGGVRS
GNITYGHRIHGAGPLTVARAGDYERVIREQGGVTPVGEERRNAVVKGGNALAVAAGGKVI
WKDSLLDEVQGLVEHPVPCLGNIDPSFLELPREVLLTSMESHQKSFGVEDAEGRLMPHFL
TVLNLTPLDGDLVRKGWERVLRARLEDARFFWKTDLASSFDAWLASLDNVIFLGPLGSMG
DKTRRLEQLCAWLAAEVGFDDATAAARAGRLSKGDLVSGMVGEFDTLQGIMGGIYARRMG
EAEAVAAAIAEQYLPAGPDSPVPSSMCGALLSIADKADTLAGCFGLGMIPTGAADPYALR
RCVLGIARIILEHGLQLDVRGLFAKAFALYGERAWKLAPEDALVKLDEFFMARLRNLFIA
NGYETLLVEAVLAAGCDDVRSAGARLEALAAFSRRDDFASAVLTFKRAANIIRKQGGDSD
VALDGAWKADLLVEDAERQLAASLEAMFPRFDGLWAEGDYPALFGLLGELRPVVDGFFEG
VMVMSDDAALRTNRLNLLQALVGRLSRLADFGALQM