Protein Info for DVU1860 in Desulfovibrio vulgaris Hildenborough JW710

Name: cutE
Annotation: apolipoprotein N-acyltransferase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 signal peptide" amino acids 6 to 20 (15 residues), see Phobius details transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 81 to 106 (26 residues), see Phobius details amino acids 119 to 142 (24 residues), see Phobius details amino acids 154 to 177 (24 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 474 to 495 (22 residues), see Phobius details PF20154: LNT_N" amino acids 14 to 176 (163 residues), 93.5 bits, see alignment E=1.6e-30 TIGR00546: apolipoprotein N-acyltransferase" amino acids 57 to 450 (394 residues), 319.6 bits, see alignment E=1.7e-99 PF00795: CN_hydrolase" amino acids 235 to 454 (220 residues), 116.1 bits, see alignment E=1.8e-37

Best Hits

KEGG orthology group: K03820, apolipoprotein N-acyltransferase [EC: 2.3.1.-] (inferred from 100% identity to dvu:DVU1860)

Predicted SEED Role

"Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE" in subsystem Phosphate metabolism or Copper homeostasis: copper tolerance (EC 2.3.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72AY0 at UniProt or InterPro

Protein Sequence (502 amino acids)

>DVU1860 apolipoprotein N-acyltransferase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MHQFLTPLVAILGLWLGFPNPLGQVPLLALLYPAALYACALRASTWQTALRSGWLTGMTA
ASACLYWLAVPVHDFGDLPWVLAVPCAVVIGAYVGLYAGLFCMATHLFRDRTSPLRRALL
AGVLWFLLEWLRGVLFTGFPWLSLSSAFVPWPVAVQFASVVGGYGLSGIMAAIACLAYES
LHGRQTSLCAATLSGFTLVICAWGIMTLSTPLPQSSPFGALMIQGNINQDQKWEAAFQKG
TVDKYLALTRQALGGERPRLVIWPETSMPFYFQEHKTYGPVVRDFVKENNIALLIGTPGY
DRKTGAGYALFNRAYLLGADGETLGHYDKEHLVPFGEYLPPGLNLPFLAKLLQGVGDFTP
GTRTQPLKLGDLALGMLICYESIFPELALQRVADGANVLVNISNDAWFGFTAAPEQHIQL
SAMRAVEQGRFLLRGTNTGITAAIDPHGRIIGRSNVFVDAAVFVTASPLSSRTVYFHIAA
WLPLAGVALALLLLLRPVRPSA