Protein Info for DVU1812 in Desulfovibrio vulgaris Hildenborough JW710

Name: coxB
Annotation: cytochrome c oxidase, subunit II, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 14 to 39 (26 residues), see Phobius details amino acids 60 to 78 (19 residues), see Phobius details TIGR02866: cytochrome c oxidase, subunit II" amino acids 10 to 198 (189 residues), 164.8 bits, see alignment E=9.5e-53 PF02790: COX2_TM" amino acids 13 to 73 (61 residues), 25.8 bits, see alignment E=2.4e-09 PF00116: COX2" amino acids 116 to 188 (73 residues), 50.5 bits, see alignment E=4.6e-17 PF00034: Cytochrom_C" amino acids 306 to 400 (95 residues), 30.9 bits, see alignment E=1.4e-10

Best Hits

KEGG orthology group: K02275, cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 99% identity to dvl:Dvul_1348)

Predicted SEED Role

"Cytochrome c oxidase polypeptide II (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72B26 at UniProt or InterPro

Protein Sequence (426 amino acids)

>DVU1812 cytochrome c oxidase, subunit II, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MYPQSLSPVQQVDLAFYVIFGVSAIMLLGITATMLWFVWRYDHRRNPVATEIPGSVLAET
AWTLIPTLIVMALFYYGWAGYKALRTVPADALEVGVKARMWSWIFEYPNGKRSSVLYVPA
GKPVKLDMTSVDVIHSLYIPAFRIKMDTVPGMQTYAWFKTDGPGEFDILCAEYCGLKHAN
MLSVVKAVEPDEFRKWLESSEAPGGKGRALLDAYGCISCHSLDGSPGPGTTFKGLYGAER
VVVLGDGSKRKIIVDEAYLRRALKDPNAELVEGFDPIMPSTEGVVPEQDFEDMIAWFMHG
NGLTREEGRRLMEQEGCLSCHSTDGSVVAGPTFKNLWGSEVDVLVDGVPKRVKVDADYVR
ESIVAPQKKLSKGWDPLMPGYDSFTPEQMEAMMDYMRSLSGTPDKAPADASSPGLHGGTS
PAGKTQ