Protein Info for DVU1765 in Desulfovibrio vulgaris Hildenborough JW710

Name: thiH
Annotation: thiH protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 295 to 311 (17 residues), see Phobius details TIGR03955: [FeFe] hydrogenase H-cluster radical SAM maturase HydG" amino acids 10 to 462 (453 residues), 505 bits, see alignment E=8e-156 PF04055: Radical_SAM" amino acids 85 to 237 (153 residues), 45 bits, see alignment E=1.3e-15 PF06968: BATS" amino acids 269 to 374 (106 residues), 71.4 bits, see alignment E=5.8e-24

Best Hits

KEGG orthology group: K03150, thiamine biosynthesis ThiH (inferred from 100% identity to dvu:DVU1765)

Predicted SEED Role

"[FeFe]-hydrogenase maturation protein HydG"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72B71 at UniProt or InterPro

Protein Sequence (464 amino acids)

>DVU1765 thiH protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MAEMKATWLDDAALEATLERNAQEDAVKAREVIAKARLLGGLDLDDVATLIALRDPELVE
EMFQTARDVKEEIYGNRLVLFAPLYISNLCSNECLYCAFRRSNTELDRKALDMDAIADET
RLIVQQGHKRILLVAGESYPREGFDYVLRAIDAVYSVHEGTGEIRRLNVNVAPLTVEQFR
NLKARDIGTYQLFQETYHRGTYAKVHLAGPKKDFDWRATAMDRAMEAGIDDVGIGPLFGL
YDWRFEVLATLRHAQHLEEAFGVGCHTISVPRLEPACGSDMASNPPRPVSNADFMRLVAI
LRLAVPYTGIIMSTRESAEMRTQTLALGVSQISAGSRTNPGGYAENEREEAAQFQLGDHR
SLSEVIADVGSMGYIPSFCTACYRMGRTGHDFMDLAKPGLIKQKCGPNALATFKEYLLDY
GTPEARAVGESVIAADLGKLDEKTRRVAERLIARVDEGRRDVFV