Protein Info for DVU1747 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 981 PF13589: HATPase_c_3" amino acids 27 to 139 (113 residues), 43.3 bits, see alignment E=5.9e-15 PF02518: HATPase_c" amino acids 872 to 974 (103 residues), 40.7 bits, see alignment E=4.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU1747)

Predicted SEED Role

"Exonuclease SbcC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72B89 at UniProt or InterPro

Protein Sequence (981 amino acids)

>DVU1747 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLNTASFQTRARAIDHLGRGQIADAPTAISELWKNAYDAYARGVELHIHSGNVVVASICD
NGHGMDAETLSSKWLVVGTESKVASPVPVEDRFGLPERARLGEKGIGRLSAAFLSPVTLV
VSKRVGQPYAALLVDWRFFENPYLFINDVRFPLVEFGELKEFPALFAQMFEELKANLQWG
SASPHTAHLAAAWDRFDAIEREQNPNAPTTREAILSLSPEGLIKWDHFSPWWQLMHKAVE
GDDVHGTALFTIGANTELACWVTDDEYESPDIQKVKETLTETLVSFVDPFEDTPIAFDYA
VVVHKPGKADFIPVSSEEVFDIQELRSLEHVIEGEFDTAGNFQGRITAFGKDRGECFLPS
PSVFTQRGKDSVGPFRFCLGTFEQDKKNTTHSDEEFEYHSSQVNKYGGICIHRDGLRVMP
YGREDGDLFRMEFRRSKHAGREFFVYRRSFGRLAITSQHNPNLKDKAGREGLVVNKARRE
FERLVINLLMYVAREYFGTASTIRNQELPGIQKARQRQMRAAETARKRNQKNFVRALKEK
LPLALEASTRAEAGADKLEQTLACKAYDDLPAIKMELDALQGLRDDLRIPNRPDELGSQE
EDYRRYRDAYALFCATIDKLKSMLARCEAEGLLGDPKRIATSKFYSNEARISSQIGKALS
TITSSLDALRTTWEENAREDRTAYRRKSTEFVSMLEAGQGLTPVLDYLDKVHTELSDELN
LKYDGIIHSLEQLVEGVDLEGAFFHVDEVNRSLEEKVSMLNSVAQLGISVEIIGHELEAL
ESQVTRYLKLMPKEVRALKSYTLAFEAHRALVDRLRFLAPLRKTSYRSRIAISGKEIAKY
VKEFFGTTFEQCRIQFEVTPAFEGFSIRDLPSRIYPTFINLVNNALYWVQRGERRIIRLD
FVQGKAIVADSGPGVDEDDQKHLFELFFTKRTNGRGVGLYLCRENLAVARHSIRYATDND
PEVLEGANFIIEFHEVEHVSR