Protein Info for DVU1685 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: conserved hypothetical protein TIGR00046 (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 TIGR00046: RNA methyltransferase, RsmE family" amino acids 10 to 228 (219 residues), 87 bits, see alignment E=6.1e-29 PF20260: PUA_4" amino acids 17 to 63 (47 residues), 42.4 bits, see alignment 6.1e-15 PF04452: Methyltrans_RNA" amino acids 71 to 231 (161 residues), 126.6 bits, see alignment E=7.3e-41

Best Hits

KEGG orthology group: K09761, ribosomal RNA small subunit methyltransferase E [EC: 2.1.1.-] (inferred from 100% identity to dvu:DVU1685)

Predicted SEED Role

"Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-)" in subsystem Heat shock dnaK gene cluster extended (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72BF1 at UniProt or InterPro

Protein Sequence (249 amino acids)

>DVU1685 conserved hypothetical protein TIGR00046 (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MRTFFLPSEQWSPPYALTGQEARHLTKVVRVHAGDLIRLLDGAGREGVFRVTGTSRNSVE
LTPESITTHPEPVSRAVLAVGWGKAVRRSWLMEKAVELEASAIWLWQAEHSQSPVPDDIK
ESWLAQMVAGAKQSANPWLPALQTLPGGIEELLRASSDFERRFMLWEGETPEALLEAKDV
GGVGTTLYVVGPEGGFSAREVKALREGGMMPVSLGQRVLRWETAALLCLGLHWWGRQKPT
AGATVEEHP