Protein Info for DVU1430 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: peptidase, M16 family (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00675: Peptidase_M16" amino acids 42 to 182 (141 residues), 116.2 bits, see alignment E=1.3e-37 PF05193: Peptidase_M16_C" amino acids 191 to 365 (175 residues), 101.4 bits, see alignment E=5.6e-33 amino acids 632 to 802 (171 residues), 72.3 bits, see alignment E=5e-24

Best Hits

KEGG orthology group: K07263, zinc protease [EC: 3.4.24.-] (inferred from 100% identity to dvu:DVU1430)

Predicted SEED Role

"peptidase, M16 family"

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72C54 at UniProt or InterPro

Protein Sequence (868 amino acids)

>DVU1430 peptidase, M16 family (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MRIAALFTCIIGVFMLATSVQAAQPADITRLSNGLTVLVLKDDRFPLASLRLYVHAGSAF
ETPEEAGISHLLEHMVFKGTVKRPKGQVARDVESVGGYLNAATSFDYTVYLTDMPSTQWK
LGMDVLRDMAFEPALDPAELESEKDVVIAELQRGEDSPDSRIFQSLQAGTLKGTTYERPI
IGYRETIRATTADTMRAYIRKHYQPQSMLLTVVGNVDPAEVRAEAERLFGGLTNDQNITP
PAAIDARAFAHGPVVNVEHGPWKKVYLGVALPVPGLKALQAAQLDMLSQLLGGDPTALLY
RTFKYEKQLVDDISVANYSFERVGMLYITAELDADKVETFWKELTTMLAGLKADAFTEQE
FERARLNIEDGLYRSKETVAGLASKEGYFQFFSDGPQGEANYLQAVRDVERPQLEALIRD
WLRPERLTVSVLLPEGTKAPALAATLKSTWPSKGKAAEEGNAAAVGKTETVDLGGGRKVV
LIPDTTLPYTALDMVFSGGNALLDQNRQGLAALTASVLTKGTLKHDAPTLEAFQSDRAAS
LGASAGRRTFTLSLREPSRFDGDMFGLLHEVLTTPALAPDEVAREKRNQVASIRAREDQP
LGLAFRHLTPFLFPGHSYGFYHLGQPETVEGFTRDDVKAFWARQAAQPWVMSVAGSFDRE
AVLRFAKSLPAPSGKPVSLDAPAWTPEKALDLRLPERNQAHLLLVFPTVGLAHKDTPALE
LLQSVLAGQSGLLFRDMRDKQGLGYTVTAMNWQSDLAGFMVLYIGTEPGKLEQAEAGFRK
VIDQLHATALPDEELRRGKNQMRGDYYREHQRLGSRSSEAAMLTSQGYPLLFNREVIDKA
EKLAPSDLERVARTYLDMNKVRVVKVLP