Protein Info for DVU1271 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: general secretion pathway protein F, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 transmembrane" amino acids 178 to 202 (25 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 271 to 283 (13 residues), see Phobius details amino acids 375 to 399 (25 residues), see Phobius details PF00482: T2SSF" amino acids 72 to 195 (124 residues), 93.6 bits, see alignment E=4.6e-31 amino acids 275 to 397 (123 residues), 96.9 bits, see alignment E=4.6e-32

Best Hits

KEGG orthology group: K02653, type IV pilus assembly protein PilC (inferred from 100% identity to dvu:DVU1271)

Predicted SEED Role

"Type IV fimbrial assembly protein PilC" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72CL2 at UniProt or InterPro

Protein Sequence (408 amino acids)

>DVU1271 general secretion pathway protein F, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MASFSYTARNENGVKMEGVIDAESTEAARAILFSRGYVPLEVKAGAGGGFSLGLGALADA
LSPIPPKELILFTKQFRTLFQAGIPITQLLQVLQNQTEHKRLKAIAAEMSQAIMGGATLY
DAFRAHPKVFSELYCSMMRAGEASGALGEVMDRLVYLLEHEHKIRSDIKSALRYPKMVMG
ALAVAFFVLLNLVIPKFVLIFSQARITLPWPTKIAIGMHYVFSTYWYVVLAVVVAGTVAY
KYWVRTEDGRYWRDRLVLRLPGVGPVIQKSVMARFASIFAILQSSGVSVLDALDVLNNTI
GNAAIAREFTRIQDQLREGRGIAEPLRTARFFTPLVVNMVAIGEESGSLDAMLNDVARHY
DEEVEYAVAGMAEAIGPVLIVALAAVVGFFALAIFMPMWDLTQMAGKR