Protein Info for DVU1252 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: membrane protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 758 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 108 to 140 (33 residues), see Phobius details amino acids 152 to 174 (23 residues), see Phobius details amino acids 220 to 236 (17 residues), see Phobius details amino acids 242 to 262 (21 residues), see Phobius details amino acids 269 to 295 (27 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details amino acids 384 to 414 (31 residues), see Phobius details amino acids 426 to 446 (21 residues), see Phobius details amino acids 458 to 481 (24 residues), see Phobius details PF02516: STT3" amino acids 96 to 160 (65 residues), 38.1 bits, see alignment E=1.4e-13 PF21436: STT3-PglB_core" amino acids 506 to 623 (118 residues), 45.8 bits, see alignment E=9e-16

Best Hits

KEGG orthology group: K07151, dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC: 2.4.1.119] (inferred from 100% identity to dvu:DVU1252)

Predicted SEED Role

"Oligosaccharyltransferase PglB (EC 2.4.1.119)" in subsystem N-linked Glycosylation in Bacteria (EC 2.4.1.119)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.119

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72CN1 at UniProt or InterPro

Protein Sequence (758 amino acids)

>DVU1252 membrane protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTRLRGTLSVCIDAFPAWTRPLALAFVVYALSFGMRMLEYPAWQNPEYMLDGEYLLATHD
AYHWIAGAEGFEFGAGHPMSELVRLAAAFTGTTPAAVGFWLPPVMASLVAVGVFGWAAAL
GGVEAGVCAGVLASLAPGFLARTLLGYCDTDLVTLLFPLLMGLGPAFWMARFMFTPLQVA
RRLLARRTGTSDVVPDAVAVMMTSRGEADDDWHGGALSPRWLALLAGSGLVGSWGAEWHS
LFPYLIRYDVVLLFGCICVFGRPGMRRALLVGGLAYALPMLVGAWGLLFALALGWGLHRA
DARFMAFVRGRALPVAGWCAVAVLLFDPDVFRMFLNSIAGYVKRSGDPSPGAGGDDPLVY
PSVAQSIIEVQDLSLSEVLSYFHPWLWVALAGLGGFVPLLLARPAAFFLLPLGVLSFLSV
KLGGRMVMFGAPVLALGFALPMVWGVQRVLRHDLRTGWVRLALSAVLLVIVATPFVDLLP
AMTQGPIINKRHAEALRHIRTATPEDSMVWIWWDWGYSAHHFAHRRTIADGASHGGPSLY
VPAAVFSTANPRFAWQLIRYTAERGGIPGSVFEGMGGAQAQELVHRLGIEKMTFADAPRQ
YLVVSYDMLRLGFWITNFGTWDFLSREGKGYAISSIPQQLSYSLDTGEVQVQGNTTGVLA
STIDVFDEGQLERRDYIVRQGGSGNAIADYAARQRNIESRRNIHFLFNKVTGEKLVLDDR
LYNTVMVQLLLCSPDDTRFAPYFKLIYDNVYARVYEVR