Protein Info for DVU1207 in Desulfovibrio vulgaris Hildenborough JW710

Name: fabH
Annotation: 3-oxoacyl-(acyl-carrier-protein) synthase III (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 310 to 328 (19 residues), see Phobius details TIGR00747: 3-oxoacyl-[acyl-carrier-protein] synthase III" amino acids 7 to 330 (324 residues), 378.5 bits, see alignment E=1.3e-117 PF00195: Chal_sti_synt_N" amino acids 38 to 171 (134 residues), 37.5 bits, see alignment E=2.7e-13 PF08545: ACP_syn_III" amino acids 108 to 177 (70 residues), 83.6 bits, see alignment E=1.1e-27 PF08541: ACP_syn_III_C" amino acids 241 to 330 (90 residues), 125.1 bits, see alignment E=1.5e-40

Best Hits

Swiss-Prot: 100% identical to FABH_DESVH: 3-oxoacyl-[acyl-carrier-protein] synthase 3 (fabH) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K00648, 3-oxoacyl-[acyl-carrier-protein] synthase III [EC: 2.3.1.180] (inferred from 100% identity to dvl:Dvul_1850)

MetaCyc: 41% identical to 3-oxoacyl-(acyl-carrier-protein) synthase III (Agrobacterium fabrum C58)
RXN-22027

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.180

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72CS6 at UniProt or InterPro

Protein Sequence (330 amino acids)

>DVU1207 3-oxoacyl-(acyl-carrier-protein) synthase III (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTSPSLLRGFGAYAPERILTNADIESMVETTDEWITTRTGIRQRHVVAPGQTTSDLAVEA
ARAALADAALDTADITHVLVATCTPDASCPNTACIVARKLGMTGVMALDCNAACSGFLYG
LELAQGIVAARPASRVLLVAAEALSLRCNWKDRTTCVLFGDGAGATVVTADVDATQGTAV
LEDSIVTSDGSLGDLLTIGGGTANPYAIGDSVGEEYFVRMQGRDVFKHAVRSMTQVCNDL
LARNGFTTEDVDLVIPHQANLRIIEAVGDRLGFASEKVFVNVHDFGNTSAASIPLALADA
RAQGRIRPGMRVLLTTFGGGFTWGAALLRF