Protein Info for DVU1157 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: sensory box histidine kinase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1085 transmembrane" amino acids 48 to 72 (25 residues), see Phobius details amino acids 78 to 101 (24 residues), see Phobius details amino acids 119 to 145 (27 residues), see Phobius details amino acids 155 to 177 (23 residues), see Phobius details amino acids 185 to 208 (24 residues), see Phobius details amino acids 223 to 244 (22 residues), see Phobius details amino acids 264 to 294 (31 residues), see Phobius details amino acids 315 to 336 (22 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details amino acids 395 to 415 (21 residues), see Phobius details amino acids 435 to 458 (24 residues), see Phobius details amino acids 464 to 485 (22 residues), see Phobius details amino acids 576 to 598 (23 residues), see Phobius details amino acids 610 to 629 (20 residues), see Phobius details PF02518: HATPase_c" amino acids 965 to 1072 (108 residues), 86.9 bits, see alignment E=6.6e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU1157)

Predicted SEED Role

"Two-component hybrid sensor and regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72CX6 at UniProt or InterPro

Protein Sequence (1085 amino acids)

>DVU1157 sensory box histidine kinase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MQTPLHDARSLSIKALKRRRIYNALVVNEAIEDYSLRSAAKSFRRWPCWLLANTALGGIT
FMALEAIGALLVLNNGFVNSTLAILCVSAIIILTGLPISYYASRYNVDIDLLTRGAGFGY
YGSTVTSLIYASYTIIFFAIEAAIMAKALSVGLGIPIHLGYLISSVVIIPLVFYGITFIN
KLQLYTQPVWVVLTVILFAYILTCDPTALDAWVEYTGKDGMAAGFDPLLFGGALSVLFSL
VPQIGEQVDYLRFLPDKTPENKGAWWLSMAAAGPGWIVVGCLKLLGGSFLAVYFMQKAGA
RISDALDPVNLYYNGFSALLGTGGLTLATTTIFVIVCQVKINVTNAYAGSLAWSNFFSRI
SHSHPGRALWLVFNVTISLLLMQFGVFYLLHSVLMVYAMFAVSWVGALFADLVILKPLGL
SPRHIEYKRANLYNLNPVGFGAMLMASGVSLLCYRGAFGPLPQAFAPLVALVVSVPTAVG
IALLTGGKYYMARKAEPVSLTASTTCTTCGNSYEAGDMVYCPAYDEPVCSLCCSLDSVCG
GFCKRLAHATAGRKEAWDEAKIPLPFLHLSRRAKIFCLHFFNIFCAQALIFVLCYAYFRN
TGLGSPLLEEICATIFVFSSLINGIWVWWSSLIQETRLRTEDELDRHIHELNEEVKRREA
MSAQLAESASQQRLILENASIGIAYVREKRVVWGNNRFMRLCGLADDLRQGATMPLGTIL
AKLGTGTDIMNEVRAAHVSGGKFDVELPIFHSSTQQYWCVLSVSVVDPVHVEYGSIWLLD
DITERKLAEEKLRHSEERLKELNESLESQVRLRTEELERSFESVRQADKMASLGILVAGV
AHEINNPSSFIRMNIGLLQSIWDDSIHILDRESKKEDLWIAGMPFDYARKSIPKLLRGIH
QGAERVSTIICNLKDYARQVPLDMSGSVDLNKAVHSALELLTTPLRKATNRLVVETEDGL
PAFRGDQRRIEQILVNLIQNAYQALQNRRQGIHMRTYRADGTVCFEIVDEGHGITQEQLT
HICDPFYTTKRDQGGTGLGLSVSAGIIKEHGGNMQFSSEPGRGTTVTLRFQAPERPPLQQ
QEPLP