Protein Info for DVU1065 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: peptidyl-prolyl cis-trans isomerse domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 162 (162 residues), 180 bits, see alignment E=1e-56 PF13623: SurA_N_2" amino acids 2 to 138 (137 residues), 107.9 bits, see alignment E=1.3e-34 PF09312: SurA_N" amino acids 40 to 161 (122 residues), 35 bits, see alignment E=4.3e-12 PF13145: Rotamase_2" amino acids 245 to 380 (136 residues), 59 bits, see alignment E=2.6e-19 amino acids 399 to 488 (90 residues), 27.1 bits, see alignment E=1.9e-09 PF13616: Rotamase_3" amino acids 264 to 364 (101 residues), 94.9 bits, see alignment E=1.5e-30 PF00639: Rotamase" amino acids 272 to 364 (93 residues), 96.6 bits, see alignment E=4.3e-31

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 100% identity to dvu:DVU1065)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72D64 at UniProt or InterPro

Protein Sequence (629 amino acids)

>DVU1065 peptidyl-prolyl cis-trans isomerse domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLDVIRGHAQSWGVKVAFGLIIVVFVFWGVGSMQEGPTSVVATVNKKPIVIRDFIREYER
QVESLRTRFPGVTADELKKLGLKRQVLQQMVAETLMQQEAERLGITVTPYELRAAIDQIP
AFRDASGKFDPETYKKVLKAQQTVPGRFEEGVRKDMLGRKMRALVTAGAVVTDAEARDMF
TYAQEKRSIDYVLFPLDEYAAAASIEDAALQAWYDSNKARFTEPQKVRLDFVRISAESLA
AGIDIPETAIAAFYAENAASYFMQPERVRARHILVRVPEGADEATVRKAEERIADAAAQI
KAGKDFAAVAAKVSEDGSARNGGELGWFGRGEMVKPFEDAAFGLKPGEVSAPVRSQFGFH
LIKSEGHEAQRQKALDEVRNEIRKRLAEEKAIEKVHDSLDNALELVSAGKSVDEIAAQLK
LERQTSEPLTRESASATLGLKPADVTLAFSAPAGTVIDTPLEAEGGYIIARVAEVAPERI
PGFDEVRDKVVVAVREDEGARLALKAADEALAGVRDGQLPGALASRVKTSPLFGRDGNIP
GLGVDPALAAAAFSAEKGVWSDKAHATPQGVVVLRVHEVVRPTDAQWQAVASTVKETILA
AKREEMFRAFLTTLHAKGKVEVKDASVLE