Protein Info for DVU1049 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: ABC transporter, ATP-binding protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 PF00005: ABC_tran" amino acids 19 to 149 (131 residues), 103.3 bits, see alignment E=1.7e-33

Best Hits

Swiss-Prot: 34% identical to CCMA_RHOCB: Cytochrome c biogenesis ATP-binding export protein CcmA (ccmA) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)

KEGG orthology group: K02193, heme exporter protein A [EC: 3.6.3.41] (inferred from 100% identity to dvl:Dvul_1944)

Predicted SEED Role

"ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA" in subsystem Biogenesis of c-type cytochromes

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72D80 at UniProt or InterPro

Protein Sequence (216 amino acids)

>DVU1049 ABC transporter, ATP-binding protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLLRLERVAKFYGTRLIIKDVSLTVEQGTVTLLAGANGAGKSTLLKIMAGLSRPSAGTVE
RSVPDEKLGYLGHQTFIYPDLTALENLAFWSSLHDLSADEGRLLNALDRMELKRFAHERA
GGFSRGMAQRLNLARLLLLEPKLILLDEPGTGLDVRSLGILHREIDAARKGGAGLVWISH
SVASDIVRADRVVAIGDRRVSYDGPAADYTPEVAVC