Protein Info for DVU0954 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: organic solvent tolerance protein, putative (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 764 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF19838: LptD_2" amino acids 189 to 251 (63 residues), 24.6 bits, see alignment E=1.9e-09 PF04453: LptD" amino acids 292 to 696 (405 residues), 213.4 bits, see alignment E=1.3e-66

Best Hits

KEGG orthology group: K04744, LPS-assembly protein (inferred from 100% identity to dvu:DVU0954)

Predicted SEED Role

"Outer membrane protein Imp, required for envelope biogenesis / Organic solvent tolerance protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DH5 at UniProt or InterPro

Protein Sequence (764 amino acids)

>DVU0954 organic solvent tolerance protein, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MAFVCCCVAEATTPAPVLASASVLEMRTDDAETVTWHLTADNLSTLNESKILEATGQVAL
RRGNEFFKADYARYYSTTNWVYLKGNVEVFTGTETIRAEEAEFDLRSRTGWMQKGEIFME
GPHIYFTGERVTKKWGDYYTFEKAKVTSCPPDGEAWSMNAEQAVVEIDGYAQLFGATFDV
ADTSLAYSPYMILPAKRTRQTGLLMPEYGMSTRRGVYYNQPFYWAVDDRRDVTINEYWME
KRGFMHGVEYRSREASDTAMWMRFDWLDDLTTVKNDADDPIAKDGLVRTNSERFWLRGMT
EGRLGDPDWRYKLDLDYVSDQNFLREFNSGMSGFGKSRSQLFELFGRDIRELDRNRISQG
MVYREWDRATVALSARYEQDPSLGHGNKNYSADTTVQRLPQLDVFLHKGRAFEEMPLEIE
AEAQTVYFHRRNGTQGGRTEIAPRVTLPMNSRYGSVIASMGWRQTMYNTERAKGLDGEPA
PTGDYRSLPDYNVAAFTEVGRVWDLEDGALDPATEEVGTRHWKSVYHRVQPRIEYRNIAN
VDQDRNPYYDDSDRIGPRSELVYSVTNILTRKRGTVVPARDPDSEEEYQKVAYDYLDVIR
WRLESGYDLREMDRNDDLEDYPRRPFMDMISDLRFGVFDWLSIYTRSDWSPYLGDFTRHD
QGVTFTSQRWGYISTGYSYRPKLDEYNRKRAYTGNLATLTAAVNMWGPWSAAGHMYYDFV
RQEGYERAFDLIYSNPCYKFILRYTYDVYDEGIEFLVELPGLTN