Protein Info for DVU0832 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: tetrapyrrole methylase family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 PF00590: TP_methylase" amino acids 7 to 205 (199 residues), 92.9 bits, see alignment E=1.4e-30 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase" amino acids 8 to 230 (223 residues), 198.6 bits, see alignment E=7e-63

Best Hits

KEGG orthology group: K07056, (no description) (inferred from 100% identity to dvl:Dvul_2149)

Predicted SEED Role

"rRNA small subunit methyltransferase I" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DU7 at UniProt or InterPro

Protein Sequence (275 amino acids)

>DVU0832 tetrapyrrole methylase family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MPSTSPKLWVVATPLGNPGDLSPRAREVLAAVDVVLAEDTRRTGLLFQKCGVTARRFISF
HDHNEDGRIPELLTMLQSGTTAALVSDAGMPLFADPGYRLVRACRDAGVHISVVPGPSAP
LTALAASGIAPLPFTFLGFPPRKASEQEKFFAPFTTVATTLVFFERKDRLAETLAVAHGV
LGHRELCVARELTKTHEEFIYGRLECHTAIPDDLLGEITVVIGPPEEASVSPREQVLAII
EEERADGGRTKDVAKRVQLRVRGWSVKDVYQLMQE