Protein Info for DVU0774 in Desulfovibrio vulgaris Hildenborough JW710

Name: atpC
Annotation: ATP synthase, F1 epsilon subunit (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 134 transmembrane" amino acids 39 to 52 (14 residues), see Phobius details TIGR01216: ATP synthase F1, epsilon subunit" amino acids 5 to 130 (126 residues), 125.7 bits, see alignment E=5.9e-41 PF02823: ATP-synt_DE_N" amino acids 5 to 83 (79 residues), 104.4 bits, see alignment E=2.5e-34 PF00401: ATP-synt_DE" amino acids 87 to 130 (44 residues), 54.3 bits, see alignment E=1.2e-18

Best Hits

Swiss-Prot: 100% identical to ATPE_DESVV: ATP synthase epsilon chain (atpC) from Desulfovibrio vulgaris subsp. vulgaris (strain DP4)

KEGG orthology group: K02114, F-type H+-transporting ATPase subunit epsilon [EC: 3.6.3.14] (inferred from 100% identity to dvl:Dvul_2196)

Predicted SEED Role

"ATP synthase epsilon chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72E05 at UniProt or InterPro

Protein Sequence (134 amino acids)

>DVU0774 ATP synthase, F1 epsilon subunit (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MEKSLHLEIVTPDKLVLSEQVDYVGAPGFEGEFGVLPSHIPFLSALAIGSLYYKANGKTH
HVFVSGGFAEVSDNKVTVLAESAERAEDIDIDRARKAKDRAEQRLAQIKEKVDHARAQAA
LQRALARMRVRGNA