Protein Info for DVU0749 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: DNA-binding response regulator (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF00072: Response_reg" amino acids 7 to 111 (105 residues), 35.4 bits, see alignment E=1e-12 PF04397: LytTR" amino acids 210 to 307 (98 residues), 78.6 bits, see alignment E=3.4e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU0749)

Predicted SEED Role

"DNA-binding response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72E30 at UniProt or InterPro

Protein Sequence (309 amino acids)

>DVU0749 DNA-binding response regulator (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTRLSTLLVHPDPMLRHRLRAMLEPVDFLRVLGEAAGAEEALALLNALPYGAVFLGISLA
EGPDGMEVARRLMGNRDHPALIFIADDESRAFEAFELDATDYLIFPCAADRFDRTLMRLR
QFRTHFRLAPAPGSRWREQPQAAPEELPPPAMDDLPPPGTEEGPPFETLQLPLAEDEQDT
LISALGEAVDYSQRVRPVELDKLAVSVDGKTLLIPYGEIAFVEAYEDYSYVHTADDKYLT
SYRLKNLEGRLRPHRFFRVHRKYLVNLDMVTELAAVSGGNCLLRTAGRTRIELPISRRRL
GELKQILGL