Protein Info for DVU0717 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: GGDEF domain/EAL domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 TIGR00229: PAS domain S-box protein" amino acids 11 to 57 (47 residues), 24.1 bits, see alignment 3.3e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 59 to 223 (165 residues), 132.6 bits, see alignment E=1.1e-42 PF00990: GGDEF" amino acids 62 to 219 (158 residues), 158.4 bits, see alignment E=1.3e-50 PF00563: EAL" amino acids 240 to 476 (237 residues), 237.2 bits, see alignment E=1.7e-74

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU0717)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72E62 at UniProt or InterPro

Protein Sequence (502 amino acids)

>DVU0717 GGDEF domain/EAL domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MENTTPLGNRRFEWIFMRSGGSEVPCEVTLSPVMQRGRRMLHLTARDISERKRNEAQITH
LAFHDSLTGLANRVLFLDRLAHAIATCRRAPDRNFAVLFIDLDRFKVINDSLGHAAGDGL
LSIIASAIAANIRETDTVARISGDEFTVLVHEPPSPRFAIKMARRILERIKQPLTIEGFE
LVISASMGIVIGNSGYTDPHQVLRDADIAMYKAKRAGKDKLRVFGSRMHEQALHAMRLEN
DLRQAIDNGDLSCHYQPIVNLESGALEGFEALARWQHPTLGNIPPSTFIPIAEDTGRIIP
LGRAMLHKACAFAASIRGTLPQGDPVIHVNLSPRQFLSRQRLREVEAALDATGLPPELLV
LEITESLLMENPRVAKSIMAGLKEIGVRLSLDDFGTGYSSLGSLQDYPLDSVKIDRSFIR
AMNDGRDAEHIVRAILKLVSHLRLEAICEGVETTMQAANLMAFGATRMQGFLFAKPMPSE
KARSLLERLALGERFTLTGMGS