Protein Info for DVU0655 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: PHP domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 PF02811: PHP" amino acids 7 to 77 (71 residues), 54.2 bits, see alignment E=1.1e-18

Best Hits

KEGG orthology group: K07053, (no description) (inferred from 100% identity to dvl:Dvul_2305)

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72EC3 at UniProt or InterPro

Protein Sequence (288 amino acids)

>DVU0655 PHP domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTPRFIDLHTHTTASDGSDSPADLVRKATEAGLAAVAVTDHDTVAGLDEAVAMGHETGIE
VVRGCELGVRSEYGEIHILGLWLPEKPETLLDAMKELRRHRNERNERIVDNLRTLGMDIT
YEEVRALSGGVSVGRPHIALALLRHGYIRTPQEAFDRFIGPGAPAYAPKKVFSPAEGVRL
LASCGATVAIAHPMLLRCPEEWLDDTVADLKVAGLDAIEAYHSEHSHKDERRCVDIADRH
GLVLTGGSDYHGKAKPAISLGRGRGGLRVTTHVLDNLKRHRRERGLPV