Protein Info for SOA0100 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF07969: Amidohydro_3" amino acids 74 to 564 (491 residues), 434.4 bits, see alignment E=8.8e-134 PF01979: Amidohydro_1" amino acids 494 to 563 (70 residues), 28.4 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 100% identity to son:SO_A0100)

Predicted SEED Role

"Predicted metal-dependent hydrolase with the TIM-barrel fold"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E840 at UniProt or InterPro

Protein Sequence (604 amino acids)

>SOA0100 conserved hypothetical protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MKFISSVVVCLSLSPFVHASSPPKTDAETIYIGGNIVTVTDSAPTAEALAVKNGRILALG
KTSDLLKLKGSNTQVVNLNGKTLIPGFIDGHGHVFNTGIQALSANLLALPDGHVNDIAAL
QRELTVWAKKPENAKHGIILGFGYDDSQLAEQRHPTRQELDAVSNDIPILIIHQSGHLAT
LNTKALTLAGFNSNSKDPEGGKIRREADGKTPNGVLEETAFFGTLLPLFAKLNETENEAI
FNAGMKLYASFGYTTAQEGRASSSAVKTMYNLAQQQKLPIDVAAYPDIQTAQEVIAPPYF
SAHYNNGFRVAGAKLNLDGSPQGKTAWLTKPYLIPPVGQEPDYKGYPSMSDEKAAEYIAL
AQSKGWQLLTHVNGDAAIDQLLKGIEASEKIYGKPDRGFVAIHAQTARQDQIERFKRLGV
FPSFFPMHTFYWGDWHMDSVLGKERAQNISPTGWARELGMIYTSHHDSPVALPNSMRVYS
ATVNRISRTGRVLGPAQKASPLEGLKSQTIWAATQYKEEESKGSLEVGKLADLVILSDNP
LTIPAEKLADIQIIETIKEGKTVYKRNEQQTSDKVNHGGCIDSPRCQAVATTAMVAAGVL
HHSH