Protein Info for SOA0012 in Shewanella oneidensis MR-1

Name: umuC
Annotation: umuC protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF00817: IMS" amino acids 5 to 151 (147 residues), 122.8 bits, see alignment E=1.7e-39 PF11799: IMS_C" amino acids 244 to 358 (115 residues), 62.5 bits, see alignment E=7.3e-21 PF13438: DUF4113" amino acids 367 to 416 (50 residues), 76.8 bits, see alignment 1.6e-25

Best Hits

KEGG orthology group: K03502, DNA polymerase V (inferred from 100% identity to son:SO_A0012)

Predicted SEED Role

"Error-prone, lesion bypass DNA polymerase V (UmuC)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E897 at UniProt or InterPro

Protein Sequence (418 amino acids)

>SOA0012 umuC protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MFALVDANSFYCSCEQVFRPDWRGKPVVVLSNNDGMVVAANRQAKEAGIPKFVPYFQIRD
LCQKKGVIALSSNYELYADLSAKMMQIIGRFAPEQYVYSIDESFLSFTRCYPAITCLKTQ
AQAIRRAVWKEARLPVCVGIGSTLTLAKIANHAAKKISGYAGVCVIESEPQRLAILQQMP
VGEVWGIGRRLSAKLTLMGITTAAQLAAMPPGLARKQFSIEIERTVRELNGQVCKQWDEA
RADKQQIFSTRSVGERIIDIDALQQALCKHAGIAAAKARQQGSSCKSMLVFASNSPHDER
PVSYKAVVQFPCPTSSTAEITAAVSRVLPQVFRSGVRYYKIGVGLIELMPTKHIQYDLFH
APTENPALMQTFDKLNQRYGSDCIFMAAQGIEHKWAMRRDKLTPQYTTKWLNLPKVQC