Protein Info for SO4385 in Shewanella oneidensis MR-1

Annotation: von Willebrand factor type A domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00092: VWA" amino acids 73 to 238 (166 residues), 72.1 bits, see alignment E=7.1e-24 PF13519: VWA_2" amino acids 75 to 178 (104 residues), 51.6 bits, see alignment E=1.3e-17

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 100% identity to son:SO_4385)

Predicted SEED Role

"Putative membrane protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E999 at UniProt or InterPro

Protein Sequence (451 amino acids)

>SO4385 von Willebrand factor type A domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNLKYLLSALAFLSCSTFTLNVSAMPTDNEAKIITKAELSAPIILENTQENNYLKISLTG
FKQDETEKSPINLSLVIDRSGSMSGDRIEKAREAAIMAINMLKDDDIVSVIAYSDNAYLI
IPATKVKNKNEMIKIINDTIKPGGSTALFAGVSKGITEVNKFIKKNQVNRIILLSDGQAN
IGPSTTKELADLGQVAGKQGIAVTTIGLGNGYNEDLMTALAGFSDGNHAYVENSADLETA
FVREFNDVMSVVAQEVVVTIKLQDGVKPVRLLGRDGDILGNNVTVKMNQLYSNQEKYVLL
EVVPPKGKESENKLLADVSISYDNLKTHHKDTFNDQVNISYSKSPQAVQAAVKEEIVVDS
AIQKANIENTRAIKLLDEGKKDEANKIIQQNAADMDALAISVNTPAAKTKAILGMEANKK
LATEVETKDVSSSRKSLKESTYSTEKQQIKK