Protein Info for SO4350 in Shewanella oneidensis MR-1

Name: ilvY
Annotation: transcriptional regulator ilvY (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 PF00126: HTH_1" amino acids 3 to 62 (60 residues), 66.1 bits, see alignment E=2.2e-22 PF03466: LysR_substrate" amino acids 88 to 290 (203 residues), 125.8 bits, see alignment E=1.6e-40

Best Hits

Swiss-Prot: 53% identical to ILVY_SALTI: HTH-type transcriptional activator IlvY (ilvY) from Salmonella typhi

KEGG orthology group: K02521, LysR family transcriptional regulator, positive regulator for ilvC (inferred from 100% identity to son:SO_4350)

Predicted SEED Role

"HTH-type transcriptional regulator IlvY" in subsystem Alanine biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E9D4 at UniProt or InterPro

Protein Sequence (290 amino acids)

>SO4350 transcriptional regulator ilvY (NCBI ptt file) (Shewanella oneidensis MR-1)
MDIRSLKLYLHLCDSLHFAKTAEQMHVSPSTLSRALQRLEEEVNAKLFERDNRSVTLTHA
GREFKLFAEQTLHHWRNLRHSIDLKQDVLRGTLNLYCSVTAAYSHLPQLLERFRQEHPFV
EIALTTGDAANALAEIQQNRADIAIAALPDPFPATLHFAKIDDVPLSLIAPTMRCAVQQQ
ISQTQIDWARVPFIIPDHGPGRRRADNWFKQMGISPNIYAQVSGQEAIASMVALGCGVSI
SPEVVINNSPVRDRIQLLPSPVSIAPFELGCCCKVKRLGDPIVNAFLEAI