Protein Info for SO4207 in Shewanella oneidensis MR-1

Annotation: GGDEF domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 625 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 186 to 205 (20 residues), see Phobius details amino acids 216 to 237 (22 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details amino acids 276 to 296 (21 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details amino acids 334 to 355 (22 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 54 to 170 (117 residues), 81.8 bits, see alignment E=7.1e-27 PF07695: 7TMR-DISM_7TM" amino acids 185 to 385 (201 residues), 129.2 bits, see alignment E=3.1e-41 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 451 to 616 (166 residues), 170.6 bits, see alignment E=1.2e-54 PF00990: GGDEF" amino acids 455 to 613 (159 residues), 161.3 bits, see alignment E=2.6e-51

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_4207)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E9Q9 at UniProt or InterPro

Protein Sequence (625 amino acids)

>SO4207 GGDEF domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MAKLGNILVLLISMFMSSAVYADTMSIDDHTPTPLNLMPWLTVTHLNTTSELADIQALPK
TKWHQFTSGDIQRLSQHNFWLTFSIQSGDESLSRILALDNPLLDKVTLYHLVGNQLINTT
YMGDTLPYQQRPLLSNIFLYPFKINANEQHTFYLHIETEGNAAVPINLWSANDLVQIAES
TAVEHGFQLGVLAAIGIFSLFIALASGSFSYSYYSGYVLCMTLLVATINGFAFRFLWPNW
PALQQLMVPMLLPLVMGFALMFTEKILQLKYYNRHMLLMCRYSAVYILLVCLLVPFTRYG
TVLYIEIVSVAVLSIIMMILAIIQAVRGQKLAKLYTIGWVSMLTGACLSSLLYLSVIELN
IKPQTPVMLGLTFEIIFMSLVLAIRYNDERKAKQRIQQEALKQAQKIRSAREEALKVEAE
TNERLEQKVQERTLELEITLRELHEVNQKLTEQSTIDSLTGVKNRSAFDKRLLAESRISR
RQETPIALLMLDIDRFKSINDQFGHLAGDQALKLIAQTLQQHLKRPTDLVSRFGGEEFAI
ILPNTTADGALQVAESIRDTVSCIGLTWEGKPIPLTVSIGVSADVIMNEQHSTELLEQAD
KALYQAKNSGRNQVKLYAPAQTEPN