Protein Info for SO4148 in Shewanella oneidensis MR-1

Annotation: HlyD family secretion protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 32 to 49 (18 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 26 to 441 (416 residues), 474.2 bits, see alignment E=1.9e-146 PF13533: Biotin_lipoyl_2" amino acids 68 to 113 (46 residues), 28.9 bits, see alignment 1.9e-10 PF13437: HlyD_3" amino acids 292 to 403 (112 residues), 68.3 bits, see alignment E=2.3e-22

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 100% identity to son:SO_4148)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E9W4 at UniProt or InterPro

Protein Sequence (441 amino acids)

>SO4148 HlyD family secretion protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNDRQLNHRSLPEHEFTQAIEAPAEKRIIKQITYFIAGSVFIMFVWSLFTNIEEIAKAKG
QVIPLGHQQVIQSFSGGTLASILVSEGDLVKKGDVLANFIAIDSQAAAEELESKQANLVL
KIERYSAFIESREANFASYLESHPNLVKGHISDLERMNNEKQAIIQSSLAEIAKSKAELA
SLDQEIPPLKHQITSAQQTINMMESIKESQAVSKLTMLESQQKLDSYIRELKSMEGKQQV
LARDIENLQRQLEQKQATLLKEVGEARTDAQAELLGITARLKSSDSQVQQNTITSPVDGI
IQSIPNTSSGSVIQPGGTVAVIVPTTPTALLEAKLSPRDIGFVSVGQKARIKIDAFDYSR
YGALDGIVKRISPSTDADEKGGVFYKVQISIDKPYFGDQPDKLELIPGMTGEADIVTGDK
TVFQYLWKPVFTNVTEAFGER