Protein Info for SO4123 in Shewanella oneidensis MR-1

Name: argS
Annotation: arginyl-tRNA synthetase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 581 PF03485: Arg_tRNA_synt_N" amino acids 4 to 91 (88 residues), 86.7 bits, see alignment E=2e-28 TIGR00456: arginine--tRNA ligase" amino acids 5 to 581 (577 residues), 579 bits, see alignment E=4.5e-178 PF00750: tRNA-synt_1d" amino acids 103 to 452 (350 residues), 441.3 bits, see alignment E=3.7e-136 PF05746: DALR_1" amino acids 466 to 581 (116 residues), 121.8 bits, see alignment E=2.5e-39

Best Hits

Swiss-Prot: 100% identical to SYR_SHEON: Arginine--tRNA ligase (argS) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K01887, arginyl-tRNA synthetase [EC: 6.1.1.19] (inferred from 100% identity to son:SO_4123)

MetaCyc: 56% identical to arginine--tRNA ligase (Escherichia coli K-12 substr. MG1655)
Arginine--tRNA ligase. [EC: 6.1.1.19]

Predicted SEED Role

"Arginyl-tRNA synthetase (EC 6.1.1.19)" (EC 6.1.1.19)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E9Y7 at UniProt or InterPro

Protein Sequence (581 amino acids)

>SO4123 arginyl-tRNA synthetase (NCBI ptt file) (Shewanella oneidensis MR-1)
MKSHIQSLLEQTIESFKQQGILPADFEARIQVDRTKDKSHGDLATNVAMMLTKAAGKNPR
ELAQLIIDNLPASAYVAKVEIAGPGFINFFIDDSALANQLQAAIGDEHLGIKLPAPQTVV
VDYSSPNLAKEMHVGHLRSTIIGDSVVRTLEFLGHKVIRQNHVGDWGTQFGMLLAYMEEL
RAANGEQAQLELSDLETFYRAAKLRFDESAEFATRARQLVVALQSGDEYCNKLWREFNDI
SLSHCHEVYERLGVSLTRADVHGESAYNADLEQVVNDLAAKGLLTESNGAKVVFQEEFRT
KEGEPLPVIIQKADGGYLYATTDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKL
AKFVREDMSLEHLGFGTMNGEDGRPFKTRTGGVVKLVDLLDEANTRALELVRSKNPDMDE
ATLAEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRA
TDVDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCGYLYELAGAFSSFYEA
CPVLAADNDEQKHSRLLLSQLTASTLQKGLNLLGIETLERM