Protein Info for SO4109 in Shewanella oneidensis MR-1

Name: mshE
Annotation: MSHA biogenesis protein MshE (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 transmembrane" amino acids 430 to 447 (18 residues), see Phobius details PF05157: MshEN" amino acids 61 to 148 (88 residues), 63.9 bits, see alignment E=1.1e-21 PF00437: T2SSE" amino acids 178 to 561 (384 residues), 435.9 bits, see alignment E=1e-134

Best Hits

KEGG orthology group: K12276, MSHA biogenesis protein MshE (inferred from 100% identity to son:SO_4109)

Predicted SEED Role

"MSHA biogenesis protein MshE" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EA00 at UniProt or InterPro

Protein Sequence (586 amino acids)

>SO4109 MSHA biogenesis protein MshE (NCBI ptt file) (Shewanella oneidensis MR-1)
MKPRLKMRLGDLLVQESIITEEQLQQALGEQRKTGHKLGRTLIDLRSITETQLLQFLSQQ
LNLPLLDISKRSIPSEVVNLIPEVQARRFRALAVEDRGDSVLVAMSDPADLQALDHLETI
IAPKKLSVAVAPEQQLLQAFDNLYRRTDQIAQIAGKLEEEYAADKMFDLASLTSSDSDNE
TTVVKLLQSIFEDAVQMRASDIHIEPGEKVLRIRQRIDGQLHETILNEVNIAAALVLRLK
LMAGLDISEKRLPQDGRFHMEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETG
MPPHILARIRKQIKRPHGMLLVTGPTGSGKTTTLYGILSELNTADRKIITVEDPVEYQLP
RINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQETVEIGLRGALTGHFVLSTLHT
NDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCHNCGVEHQPTAQEKAWLNSVSRQ
DFTHANFRIGTGCQSCNGSGYRGRIGIFEILELDEKMIDAMRTGNPQDFACAALQSPNFT
PLAESALQYLSEGMTTIEEVAKLVEDVSESQVPLSRDIISQQGVEA