Protein Info for SO4077 in Shewanella oneidensis MR-1

Annotation: TonB-dependent receptor, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 708 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF07715: Plug" amino acids 52 to 144 (93 residues), 43.1 bits, see alignment E=8.1e-15 PF00593: TonB_dep_Rec_b-barrel" amino acids 214 to 665 (452 residues), 122.8 bits, see alignment E=5.3e-39 PF14905: OMP_b-brl_3" amino acids 486 to 670 (185 residues), 28.7 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to son:SO_4077)

Predicted SEED Role

"TonB dependent receptor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EA32 at UniProt or InterPro

Protein Sequence (708 amino acids)

>SO4077 TonB-dependent receptor, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MAATALNIPHGFKCSEISTALTLALGLSFAPLAMANDNEQTQIERILVHGEQSICRNALG
SADALLKDQGVDFSEAGGVSALPVLNGMMGDRIKVLVDGADITASCANQMNPPLSYVSAN
QINSVEVVAGVSPVSAGGDNIAGVIKVNSLNPKFTDSENLSFESGEISSGYRSTSDSLLL
GAKAGIASKNVSLSYQGAYEDANSYHDGNGDKVLDTLYRAQNHALTAAWRDEKQQLAVKL
THQAIPFQGFPNQYMDMTDNKSYGALVRYLRDLENDGEFSAQLNWHSVKHEMGFFTPEKT
GKMPMNTEGSDYSYQLHWRLTMGDDSTLLLGQEYYSYQLDDIWPAVPGTMMAPNDYININ
DGERRRAAVYGEWQQNLNPLWWLSAGVRYEYVTTDTGEVQAYSNMPMMGMPNVDAEAAKA
FNAMDRSRDDNLIDATLLARYQLSAKQQLEFGLARKNRAPNLYERYSWGRGVMATTMIGW
YGDGNGYVGNPDLKPETAHTLSAAYKFNGDAWQFSTTAWYSAVTDYIDAEVIGSFNRTST
PAGKRNILKFTNEDANLYGAKFSALYLLADTDSGKWQMLGKLNITRGERDEGNEPLYQIK
PLQTELALSHQLGDWENRLAWQWVATKDRVDDRRLENETSSYSLLNLSSSIKWQELSLTF
AINNLFDTYYELPLGGVSIAEFKADSSNGFSQVAGSGRSFELGASYRF