Protein Info for SO4043 in Shewanella oneidensis MR-1

Annotation: TonB domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF03544: TonB_C" amino acids 291 to 367 (77 residues), 58.6 bits, see alignment E=3.5e-20 TIGR01352: TonB family C-terminal domain" amino acids 292 to 368 (77 residues), 40 bits, see alignment E=2e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_4043)

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EA66 at UniProt or InterPro

Protein Sequence (369 amino acids)

>SO4043 TonB domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MLYGKTLPLASLLAFTLSTSLPLNASENSFSQAYSDYQAAIKQGDNAKIEASAKRAFELG
EAQYTKDSVDLANLAMNWAGVIEKQVAPYPFEEKNLPKTAKANELYQLALSNYKKHYGEH
AAELIDPLLGAAETAPKLVLAKGLLDDTLKIAEKTKDKKLLADIKMAAFARLSNTELYTA
KVRDYAFDAYETYKEILPENALDRVKATYVVGAVEYAEKHDDKAIPLLLEVVKQFDALNF
SHPYALSAHAYLVELYERQGKRDESTAHCIAIGKMRPWADTQEQQPLFRTAPDYPMSYAR
QAKNGWVQLKFTVDEHGFVKNTEILASKGGALFEKESIEALNKWRYAPKFENGKAVEAQT
SVQMDYTIN