Protein Info for SO3870 in Shewanella oneidensis MR-1

Annotation: disulfide bond formation protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 transmembrane" amino acids 27 to 52 (26 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 173 to 197 (25 residues), see Phobius details PF02600: DsbB" amino acids 25 to 189 (165 residues), 85.7 bits, see alignment E=2.2e-28

Best Hits

Swiss-Prot: 100% identical to DSBI_SHEON: Putative protein-disulfide oxidoreductase DsbI (dsbI) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: None (inferred from 100% identity to son:SO_3870)

Predicted SEED Role

"Inner membrane thiol:disulfide oxidoreductase, DsbB-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EAM8 at UniProt or InterPro

Protein Sequence (212 amino acids)

>SO3870 disulfide bond formation protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSINEVFRSFKAQPVNQLAKIQAERPIWFVMVGAAIFLILSAIFYFQLFLAMAPCEKCVY
IRFSQSCIVIAGLIILINPRNNILKTLGLLLAWYAMIQGWIWSFELMKIHDAAHMVVDES
MDFFAAAGDAAGSACSTEPRFPLGLPLDKWLPFEFAPTGGCGEDDWALFGLNMAHYCMIA
YATFMVCLAPLTLGWFASFMTDRRNTIVYQTR