Protein Info for SO3862 in Shewanella oneidensis MR-1

Name: modE
Annotation: molybdenum transport regulatory protein ModE (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 TIGR00637: ModE molybdate transport repressor domain" amino acids 17 to 107 (91 residues), 100.7 bits, see alignment E=3.8e-33 TIGR00638: molybdenum-pterin binding domain" amino acids 122 to 189 (68 residues), 57.2 bits, see alignment E=1.3e-19 PF03459: TOBE" amino acids 124 to 186 (63 residues), 51.4 bits, see alignment E=5.1e-18

Best Hits

KEGG orthology group: K02019, molybdate transport system regulatory protein (inferred from 100% identity to son:SO_3862)

Predicted SEED Role

"DNA-binding domain of ModE / Molybdate-binding domain of ModE" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EAN6 at UniProt or InterPro

Protein Sequence (259 amino acids)

>SO3862 molybdenum transport regulatory protein ModE (NCBI ptt file) (Shewanella oneidensis MR-1)
MDLHALLTLSLGDKPFANPRRIALLRQVANTGSISQGAKLAGISYKAAWDAINEMNTTMP
EAVVTSEKGGKGGGGAKLTEFGERLLKVYSITSQVQDMALTALLDDSVDMHSLLDVMAHF
SLKTSARNQLTGRIHSIEPLGLNDSLKVTLAGGQLIQISVTHASYERLQLALNQSILLLF
KAPAVIASRDACERTGQNCVSGHLLSVTELAYKAELAIDIGGKDVIYSVMPLADIQTLVL
GQPCFACFDATQVIVASMN