Protein Info for SO3770 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein TIGR00153 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 TIGR00153: TIGR00153 family protein" amino acids 4 to 225 (222 residues), 207.3 bits, see alignment E=1.2e-65 PF01865: PhoU_div" amino acids 7 to 224 (218 residues), 209.9 bits, see alignment E=1.6e-66

Best Hits

Swiss-Prot: 61% identical to Y1603_HAEIN: UPF0111 protein HI_1603 (HI_1603) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K07220, hypothetical protein (inferred from 100% identity to son:SO_3770)

Predicted SEED Role

"Phosphate transport regulator (distant homolog of PhoU)" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EAX1 at UniProt or InterPro

Protein Sequence (226 amino acids)

>SO3770 conserved hypothetical protein TIGR00153 (NCBI ptt file) (Shewanella oneidensis MR-1)
MPVNSILGVFAKSPIKPLQEHMDKVYDCASLLVPFFEATITGNWDDAVQIRKQISLAEKQ
GDSLKREIRLTLPSGLFMPVERTDLLELLTQQDKIANKAKDISGRVIGRQLLIPQALQVP
FIAYLQRCIDAVGLAQQVINELDDLLEAGFRGREVDFVAKMINELDIIEEDTDDLQIQLR
RQLFALESELNPVDVMFLYKTIEWVGGLADLAERVGSRLELMLARV