Protein Info for SO3542 in Shewanella oneidensis MR-1

Annotation: hypothetical phosphoketolase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 788 PF09364: XFP_N" amino acids 4 to 368 (365 residues), 418.6 bits, see alignment E=2.8e-129 PF03894: XFP" amino acids 398 to 572 (175 residues), 219.8 bits, see alignment E=3.5e-69 PF09363: XFP_C" amino acids 585 to 786 (202 residues), 204.5 bits, see alignment E=1.9e-64

Best Hits

KEGG orthology group: K01621, phosphoketolase [EC: 4.1.2.9] (inferred from 100% identity to son:SO_3542)

Predicted SEED Role

"Xylulose-5-phosphate phosphoketolase (EC 4.1.2.9); Fructose-6-phosphate phosphoketolase (EC 4.1.2.22)" (EC 4.1.2.22, EC 4.1.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.22 or 4.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EBH4 at UniProt or InterPro

Protein Sequence (788 amino acids)

>SO3542 hypothetical phosphoketolase (NCBI ptt file) (Shewanella oneidensis MR-1)
MTNTHEINALKKYVRATNFLATSQIYLKQNVLHKRPLAHSDIKPRLLGHWGTCPGINFVY
ANINRLIVKHNRPFIYLVGPGHGFPAVQANLFIEGSLSHFYPETIPYNETGIEDICKKFS
AAYGYPSHANPEAPGQILEGGELGYSLSVGWGAVLDNPDLIATVLVGDGESETGPLAASW
YANRLVSPATNGAVLPIVHINGYKISGPTRMGRMSHEELDLEFRGLGYHPIIVDSEAEED
VYIQMATAMDTAYSMINDIQTRARKGEDIVKPRWPVILMRTAKGWTGVSEYNGQKLEGNC
ESHQVIVNKCATDKGHLAALDNWLASYRFQELYQINAQGELIFDADICSLIPPKHLACGR
QHLTYGGEVVRALSNPDLEKLSYGPEVPRGQRGYSMLKMGQWMRDAFKLNRDQRNLRIFS
PDETYSNQLQAVFEETDRAWQWPIESWDEDMSRDGRVIELLSENLLFGMLHGYTVTGRHG
MFPTYESFSQVVSSMADQYCKYVYASQGVHFRKPLPACNVVLSSLLERQDHNGYSHQNPS
FLGAMLEKHPKIISAYLPADANSTLVYTERAFADRDKLNILVAGKKELPQWLSLEEARKQ
AKDGVMVWDFASDENPDIVLAGCGDYVTQECMASLVIIRELLPRVRIRFVSVTELSSDGL
GSRKFKEKPWMMDEIFTQDKGVVFNYHGYPNTIKKLIFDYKGSRRFRIKGYEEEGSTTTP
FDMGVRNGTSRYHLVIDMAYKLFQQGVIDETKHVSITTDMLQRLVDHRNYIKAHGVDPVE
IENWVWTR