Protein Info for SO3491 in Shewanella oneidensis MR-1

Annotation: HDIG domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 PF01966: HD" amino acids 36 to 133 (98 residues), 29.8 bits, see alignment E=9.8e-11 amino acids 247 to 368 (122 residues), 67.6 bits, see alignment E=1.8e-22 PF13487: HD_5" amino acids 236 to 399 (164 residues), 114.8 bits, see alignment E=5.7e-37 TIGR00277: HDIG domain" amino acids 247 to 337 (91 residues), 33.8 bits, see alignment E=1.2e-12 PF08668: HDOD" amino acids 249 to 296 (48 residues), 28.1 bits, see alignment 2e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_3491)

Predicted SEED Role

"Putative metal-dependent phosphohydrolase with tandem HD motifs"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EBM0 at UniProt or InterPro

Protein Sequence (422 amino acids)

>SO3491 HDIG domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNAFLPHDFKVYMDVRHALLAVATALDFVGVDDLHHGHRVAYMAYECASVLGWPDEKKQF
AYFAGLIHDCGVSSSEEHLRLLKLMQPEDAHCHSKRGYEALLECPILDVFAPIVLYHHTP
WLELQSHDLSVFERDIAALIFLADRTDFLRARYTHGCHEELITLHESMVAENLLAHCGTL
FEPEMVNAMCQLVKKDGFWYNMDATHIELLGLEFKANHFYDKELDIGGVKQLARFLARIV
DAKSPFTFHHSEKVALLAKLVAKDCGISDTDAELLYVAGLLHDVGKLKTPDLLLHKEGKL
TKEEYSIVKRHTVDTEHTLHRFFPKSVIGEWASNHHERLDGSGYPFSKRQEQLDLPSRIL
AVVDVFQALTQKRPYRGSLSLSEIYDIMQPMVDKGQLDAGVYSILLADIDNFYHLSTQEF
QT