Protein Info for SO3286 in Shewanella oneidensis MR-1

Name: cydA
Annotation: cytochrome d ubiquinol oxidase, subunit I (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 130 to 152 (23 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 222 to 240 (19 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 423 to 446 (24 residues), see Phobius details amino acids 473 to 496 (24 residues), see Phobius details PF01654: Cyt_bd_oxida_I" amino acids 9 to 503 (495 residues), 570.7 bits, see alignment E=7.7e-176

Best Hits

Swiss-Prot: 76% identical to CYDA_AZOVI: Cytochrome bd ubiquinol oxidase subunit 1 (cydA) from Azotobacter vinelandii

KEGG orthology group: K00425, cytochrome bd-I oxidase subunit I [EC: 1.10.3.-] (inferred from 100% identity to son:SO_3286)

MetaCyc: 73% identical to cytochrome bd-I subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN0-5266 [EC: 7.1.1.7]; 1.11.1.- [EC: 7.1.1.7]; 1.11.1.- [EC: 7.1.1.7]

Predicted SEED Role

"Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EC58 at UniProt or InterPro

Protein Sequence (518 amino acids)

>SO3286 cytochrome d ubiquinol oxidase, subunit I (NCBI ptt file) (Shewanella oneidensis MR-1)
MIVEEVVELSRLQFALTAMYHFLFVPLTLGLAFLLAIMVSLYVMTDKHIYKDMTKFWGKL
FGINFALGVSTGLAMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTLVGMFFFGW
DRFSKRQHLAVTWLVALGSNLSALWILVANGWMQNPVGSVFNYETMRMEMTSFAEVVFNP
VAQVKFVHTVASGYVTGAMFVLAISSYYILKKRDLPFARRSFAIAASFGMAAILSVIVLG
DESGYKVGEAQRVKLAAIEAEWHTEPAPAAFTAVGFPNQETMETDFAVKIPYAMGIVATR
SLDEQVTGIHDLISEHEVRIRNGMKAYAMLVKLRAGDTSPELRAEFEAAKVDLGYGLLLK
RYTNNVVDATEEQIKAAAKDSIPNVAPMFWSFRVMVGLGFVMLFVFAAAFWQSTRHQIEE
NKWVLKAALFSLPLPWIAIECGWFVAEYGRQPWTISEVLPTFMSASSLTTGDLWFSIISI
SLFYTVLLVIEIFLMLKFARLGPSSLKTGRYHFEKLEA