Protein Info for SO3279 in Shewanella oneidensis MR-1

Annotation: AcrB/AcrD/AcrF family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1026 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 332 to 353 (22 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 388 to 411 (24 residues), see Phobius details amino acids 431 to 452 (22 residues), see Phobius details amino acids 462 to 485 (24 residues), see Phobius details amino acids 525 to 542 (18 residues), see Phobius details amino acids 856 to 875 (20 residues), see Phobius details amino acids 882 to 904 (23 residues), see Phobius details amino acids 910 to 930 (21 residues), see Phobius details amino acids 957 to 978 (22 residues), see Phobius details amino acids 984 to 1008 (25 residues), see Phobius details PF00873: ACR_tran" amino acids 1 to 1008 (1008 residues), 462 bits, see alignment E=5.8e-142

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_3279)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EC65 at UniProt or InterPro

Protein Sequence (1026 amino acids)

>SO3279 AcrB/AcrD/AcrF family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MIKAFVENGRLVSLVIALLLVAGFGAMSSLPRTEDPHITNRFASVITPYPGASAERVEAL
VTEVLENQLRRLEEIKLIQSTSRPGISVIQLELKDTVTDTDPVWSRARDLLADARNSLPD
DIQTPTLDDQVGYAYTAILSLVWNDSSQPRVDMLNRYAKELQSRLRLLAGTDFVKLYGAP
EEEILVQLDGYKMSQLQLTPGTIANILRSADSKIAAGEINNNHFRALVEVSGELDSQSRI
RQVPLKVDSDGQIIRLGDIATISRQPKSPADSIGLVDGEQGVFVAARMLNNTRVDIWQGQ
VKQLVDEFNIDLPANIKVEWLLEQNSYTSERLGGLVINLIQGFVIILSVLLLTLGLRNAV
IVAISLPLTALFTLACMKYIGLPIHQMSVTGLVVALGIMVDNAIVIVDAIAQRRQQGMSR
LNAVTEALHHLWLPLAGSTITTILAFAPIVLMPGATGEFVGGIAMAVMFALFGSYLISHT
LIAGLAGRFSLEGKNPIWYQHGINLPLVSGYFQASLRFALNRPRLSAILIGTIPLLGFYA
SGKMTEQFFPPSDRDMFQIELYLAPHVSLENTLSQVYLMDKQLHQIEGITQVDWVVGGNT
PSFYYNLTQRQQGATNYAQAMIKTIDFERANALIPVLQQRFDKAFPEAQVLVRKLEQGPP
FNAPVELMIFGPDLETLRTLGDEIRHILAATPDVIHTRATLSAGSPKVLLQVNEDASLIS
GLSLTNIARQVQMSTTGVIGGSVLEQTESLPIRVRLGENSREQASRLSEIQLMTPSGTAV
PLSALSHNEVQVSRGAIPRRNGQRVNTIEAYIVSGVLPAQVLNDVKDKVAAIKLPAGYRI
EIGGESAKRNEAIGNLLSNIILVVTLLLATVVLSFNSFRLTAIILLSALQSAGLGLLAVF
VFGYPFGFPVIIALLGLMGLAINAAIVILAELEELPAARMGDKAVIVSTVSSCGRHISST
TITTVGGFIPLIIAGGGFWPPFAIAIAGGTLLTTLLSLVWVPTMYLLLMTKRHSTQAATL
SPQMAS